NCISis the perfect crime show that has many heartbreaking moments, along with good ones.

It’s got a great combination of seriousness, comedy, and lightheartedness.

But with a show that’s been on for 22 years,the cast will inevitably part ways.

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Image via Federico Napoli

When Tony DiNozzo (Michael Weatherly) departed the show, some big shoes were left to fill.

Who could take over for such an influential and hilarious character?

The same can be said for when Ziva David (Cote De Pablo) left.

Mark Harmon as Gibbs wearing a ballcap outside in NCIS

Image Via CBS

She was a badass and got the job done with such style.

She and Tony are such a power couple that it’s hard to imagine how the show would continue.

Even when Caitlin Todd (Sasha Alexander) was killed, it left a hole in audiences' hearts.

Custom image from Jefferson Chacon of Austin Stowell as Gibbs leaning on a railing for NCIS: Origins

She was only there for two seasons, but she made an impact.

“Prepare yourself for an emotional roller coaster because this one isn’t missing any stops.

Then, Parker finally tracks them down.

Mark Harmon and Sean Murray looking at a computer monitor

Image via Bill Inoshita/CBS

It also demonstrates his close relationship with McGee.

Worried about McGee getting an aiding and abetting charge, Gibbs insists that McGee arrest him.

After much debate, McGee agrees and takes him to Parker.

Austin Stowell as Gibbs on NCIS Origins

To everyone’s surprise, Parker undoes the handcuffs after researching Gibbs and his supposed line crossing.

It also helped that an old friend, Tobias Fornell (Joe Spano), vouched for him.

Gibbs is free to go after this heart-racing case and his altruistic displays of sacrifice.

Gibbs and McGee sharing a chat with someone offscreen while Gibbs observes McGee on NCIS

Image via CBS

‘NCIS: Origins’ airs Mondays on CBS.

You just gotta find your rhythm.

Your rhythm, not mine.”

Mark Harmon on a boat looking to the distance in NCIS

Image via CBS

Gibbs finishes his pep talk with, “Be patient.

It’s about progress, not perfection.

Once you know the basics, the rest just comes from inside.”

NCIS season 22 Wilmer Valderrama as NCIS Special Agent Nicholas “Nick” Torres, Katrina Law as NCIS Special Agent Jessica Knight, Sean Murray as Special Agent Timothy McGee, Diona Reasonover as Forensic Scientist Kasie Hines and Gary Cole as NCIS Special Agent Alden Parker

McGee reciprocates with tears in his eyes and heads for the plane, taking him back to NCIS headquarters.

This scene hit Sean Murray hard, as he and Mark Harmon enjoyed working together.

When the audience watches this episode, there isn’t a dry eye there either.

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Follows the Major Case Response Team (MCRT) from the Naval Criminal Investigative Service (NCIS), as they get to the bottom of criminal cases connected to Navy and Marine Corps personnel.

The entire episode is chock-full of emotional scenes whereGibbs gets sentimental with his friends.

You could tell Gibbs knew he might not return after the mission.

That and the giant hole he left in his basement from the boat.

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Gibbs gave everyone a pep talk before he left, like Nicholas Torres (Wilmer Valderrama).

They hugged, but not just any hug, a hug you give someone special, a longtime friend.

He was tough, but he knew how to care for his agents and show it in unconventional ways.

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“Vivo o Muerto” airs on Monday, December 9.

Not all their memories are dark and sad, however.

Why Did Mark Harmon Decide To Leave ‘NCIS?’

NCIS

“I think for the longest time, I was just tired.

The first day, we worked 22 hours.

So I thought, ‘That’s not exactly what I thought this was going to be.’

But we had a lot of days like that in the first four years.”

“Out of Control” airs on Monday, December 9.

Co-showrunnersGina Lucita MonrealandDavid J. Northtalked toTV Insiderabout seeing Harmon return to the set for the first time in ages.

That was really special, that moment, especially when he put on his boots," says Monreal.